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KMID : 1149220160240030175
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Korean Journal of Oriental Medical Prescription
2016 Volume.24 No. 3 p.175 ~ p.193
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Analysis of experimental articles of Korean medicinal prescriptions on the diuretic effect
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Im Ju-Ha
Lee Do-Eun
Park Ki-Hyeon
Kim Soo-Min
Kang Dae-Gill
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Abstract
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Objective : Diuretics are effective on the patients with hypertension and heart failure, as well as edema by regulating the function of kidney, which is key organ to maintain the balance of the different electrolytes in the body. The present review article is designed to review the diuretic effect of Korean medicinal prescription base on the experimental studies.
Method : For this purpose, every article related to ‘diuresis’ and ‘Korean medicinal prescription’ were analysed from articles which published at domestic and international journals.
Results : 1. Representative Korean medicine prescriptions showed diuretic effect along with electrolyte excretion were Oryeong-san, Paeryung-tang, Hwangryungbokryung-tang and Daeganghwal-tang. 2. Some Korean medicinal prescription including Oryeong-san, Jueryeong-tang, Sipcho-tang distribute diuresis through the inhibition of renin-angiotensin-system. 3. Oryeong-san, Bojungchiseup-tang had a diuretic effect on the down-regulation of aquaporin water channel in the renal collecting duct.
Conclusion : Korean medicinal transcriptions have a diuretic effect through several types of mechanism such as along with electrolytes excretion, inhibition of renin-angiotensin system, and down-regulation of water channels.
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KEYWORD
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Diuresis, Natriuresis, Korean medicinal transcription, Renin angiotensin system, Electrolyte, Water channels
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